Dailey Nettles

PhD Candidate, Neuroscience

Dailey earned her BS in Neuroscience at the University of Alabama at Birmingham, training in the lab of Dr. Gwendalyn King. She is a doctoral candidate working jointly in the labs of Dr. Cristin Welle & Dr. Ethan Hughes, where she studies the role of myelin in motor cortex circuit function. She uses both chronically implanted NeuroNexus and acutely implanted Neuropixel extracellular recording arrays in mice throughout demyelination and remyelination to study single-cell activity changes. She has shown that myelin loss causes neuronal hyperexcitability that recovers with partial remyelination. Outside of lab, Dailey enjoys scientific outreach, baking, knitting, and quilting.


Education

University of Colorado Anschutz Medical Campus PhD Candidate, Neuroscience Graduate Program. 2016-present University of Alabama at Birmingham Bachelor of Science in Neuroscience, Cum Laude 2012-2016


Publications

  • Dailey Nettles, Gustavo Della Flora Nunes, Kim G. Gagnon, Ryan Williamson, Daniel Denman, Ethan G. Hughes, Cristin G. Welle. Myelin loss disrupts the neural representation of dexterous reaching in primary motor cortex. In preparation

  • Dailey Nettles, Ryan Williamson, Spencer Bowles, Ethan Hughes, Cristin Welle. Head fixed skilled dexterous reach training for in vivo extracellular recordings of primary motor cortex. In preparation

  • Closed-loop automated reaching apparatus (CLARA) for interrogating motor systems. S Bowles, WR Williamson, D Nettles, J Hickman, CG Welle. 2021

  • Fluid Jet Stimulation of Auditory Hair Bundles Reveal Spatial Non-uniformities and Two Viscoelastic-Like Mechanisms. Anthony W. Peng1*, Alexandra L. Scharr2,3, Giusy A. Caprara1, Dailey Nettles4, Charles R. Steele2,5 and Anthony J. Ricci2,6. Frontiers in Cell & Developmental Biology, 2021.

  • Motor learning promotes remyelination via new and surviving oligodendrocytes. Clara M. Bacmeister, Helena J. Barr, Crystal R. McClain, Michael A. Thornton, Dailey Nettles, Cristin G. Welle & Ethan G. Hughes. Nature Neuroscience, 2020.

  • FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function. Ann M. Laszczyk,1 Dailey Nettles,1 Tate A. Pollock,1 Stephanie Fox,1 Melissa L. Garcia,1 Jing Wang,1 L. Darryl Quarles, 2 and Gwendalyn D. King. ENeuro, 2019.

  • Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss. M.Laszczyk, StephanieFox-Quick, Hai T.Vo, Dailey Nettles, Phyllis C.Pugh, Linda Overstreet-Wadiche, Gwendalyn D.King. Neurobiology of Aging, 2017.


xiaoyu dogs.jpg

Sheena is a toy fox terrier mix and Clyde is probably a carolina dog mix.  Both are rescues from Texas.  Both dogs made their names in the neighborhood by their escaping skills early in their adoption . Clyde even earned a name “ the runaway dog”. 

Dailey Nettles