Exploring frontiers of neurotechnology

The BIOElectrics Lab, led by Dr. Cristin Welle, utilizes advanced neuroscience research tools to explore the intersection between technology and the brain. Our goals are to provide new insights into the key factors that make neural interface devices effective and to use cutting-edge neural technology to learn more about the way our nervous systems function.

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Recent Publications

Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement

Spencer Bowles, Jordan Hickman, Xiaoyu Peng, W. Ryan Williamson, Rongchen Huang, Kayden Washington, Dane Donegan, Cristin G. Welle, Vagus nerve stimulation drives selective circuit modulation through cholinergic reinforcement,
Neuron, Volume 110, Issue 17, 2022, Pages 2867-2885.e7, ISSN 0896-6273,
https://doi.org/10.1016/j.neuron.2022.06.017.

Two-photon excitation of potentiometric probes enables optical recording of action potentials from mammalian nerve terminals in situ.

Fisher JA, Barchi JR, Welle CG, Kim GH, Kosterin P, Obaid AL, Yodh AG, Contreras D, Salzberg BM (2008) Two-photon excitation of potentiometric probes enables optical recording of action potentials from mammalian nerve terminals in situ. J Neurophysiol. Mar;99(3):1545-53. www.ncbi.nlm.nih.gov/pubmed/18171710

FDA Regulation of Invasive Neural Recording Electrodes.

Welle CG, Krauthamer V (2012) FDA Regulation of Invasive Neural Recording Electrodes. IEEE Engineering in Medicine and Biology, Pulse Magazine. March-April:37-41. www.ncbi.nlm.nih.gov/pubmed/22481744